The best one line description I have seen...
"The Microsoft Office SharePoint Web application builder"
That pretty much sums up what I use SPD for.
As seen on the new Office Online sitehttp://office.microsoft.com/en-au/sharepointdesigner/FX100487631033.aspx?ofcresset=1
Until now, this content has only been available from computers that had a beta version of Office 2007 installed.